Overview

Phase 1 Study of TPX-0022, a MET/CSF1R/SRC Inhibitor, in Patients With Advanced Solid Tumors Harboring Genetic Alterations in MET

Status:
Recruiting
Trial end date:
2023-11-01
Target enrollment:
Participant gender:
Summary
A phase 1, first-in-human, open-label study to determine the safety, tolerability, PK, and preliminary efficacy of the novel MET/CSF1R/SRC inhibitor TPX-0022 in adult subjects with advanced solid tumors harboring genetic alterations in MET. The study will proceed in three parts: a dose-escalation, a food effect, and dose-expansion.
Phase:
Phase 1
Details
Lead Sponsor:
Turning Point Therapeutics, Inc.