Overview

Phase 1-2 of a CpG-Activated Whole Cell Vaccine Followed by Autologous Immunotransplant for MCL

Status:
Completed
Trial end date:
2017-12-14
Target enrollment:
Participant gender:
Summary
Mantle cell lymphoma (MCL) is a sub-type of non-Hodgkin's lymphoma (NHL) which is generally considered incurable with current therapy. Participants will receive an autologous vaccine against their individual lymphoma after undergoing stem cell transplantation. This vaccination may prolong the time which patients will stay in remission from their disease.
Phase:
Phase 2
Details
Lead Sponsor:
Ronald Levy
Collaborator:
National Institutes of Health (NIH)
Treatments:
Cyclophosphamide
Rituximab
Vaccines