Overview

Phase 1/2 Study of CISH Inactivated TILs in the Treatment of NSCLC

Status:
Not yet recruiting
Trial end date:
2027-11-01
Target enrollment:
Participant gender:
Summary
A clinical trial to assess the safety and efficacy of genetically-engineered Tumor Infiltrating Lymphocytes (TIL) in which the intracellular immune checkpoint CISH has been inhibited using CRISPR gene editing for the treatment of Metastatic Non-small Cell Lung Cancer (NSCLC).
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Intima Bioscience, Inc.
Treatments:
Aldesleukin
Cyclophosphamide
Fludarabine
Interleukin-2
Pembrolizumab