Overview

Pharmocokinetic/Pharmacodynamic (PK/PD) Study of the Combination Cetuximab/Gefitinib

Status:
Completed
Trial end date:
2008-05-01
Target enrollment:
Participant gender:
Summary
This is an open-label, phase 1, non-randomised, non-controlled trial, carried out in two centres on patients with advanced cancer expressing EGFR. Primary objective is the determination of the maximum tolerated dose (MTD) and recommended dose (RD) of the combination of intravenous Cetuximab and oral Gefitinib.
Phase:
Phase 1
Details
Lead Sponsor:
Harrison Clinical Research
Collaborators:
AstraZeneca
Merck KGaA
Merck KGaA, Darmstadt, Germany
Treatments:
Cetuximab
Gefitinib