Pharmacotherapy Dosing Regimen in Cocaine and Opiate Dependent Individuals - 8

• Status: Terminated
• Trial end date: 2010-02-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to examine two medications, modafinil and citalopram, in the treatment of cocaine dependent individuals who are maintained on methadone.

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: The University of Texas Health Science Center, Houston; University of Texas
• Collaborators: National Institute on Drug Abuse (NIDA); University of Texas
• Treatments: Armodafinil; Citalopram; Cocaine; Dexetimide; Methadone; Modafinil

Criteria

Inclusion Criteria:

• Meets cocaine abuse and dependence criteria (as determined by the SCID)

• Meets opiate dependence criteria (as determined by the SCID)

• In good general physical and psychiatric health (except for possible acute drug use related problems)

Exclusion Criteria:

• Meets diagnostic criteria for other psychiatric disorders, including other forms of drug dependence (other than nicotine)

• Current cardiovascular disease (as determined by an electrocardiogram)

• Circumstances will not allow for completion of study (on probation or parole)

• Ethical constraints of supervision do not allow confidentiality (on probation or parole)