Overview Pharmacologically-based Strategies for Opioid Substitution Therapy During Pregnancy Status: Recruiting Trial end date: 2023-05-31 Target enrollment: Participant gender: Summary This study will evaluate maternal tolerance to several BUP dose reduction strategies. Phase: Phase 2 Details Lead Sponsor: Steve N. Caritis, MDUniversity of PittsburghCollaborator: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)Treatments: Buprenorphine