Pharmacological Interaction Between Carvedilol and Methylenedioxymethamphetamine (MDMA)
Status:
Completed
Trial end date:
2011-05-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to determinate the effect of a pre-treatment with carvedilol, a
alpha- and beta-adrenergic receptor blocker, on the pharmacodynamics and pharmacokinetics of
3,4-methylenedioxymethamphetamine (MDMA, "Ecstasy"). The investigators hypothesize that
carvedilol will attenuate the cardiovascular and subjective response to MDMA.