Pharmacologic Study of Methotrexate in Patients Undergoing Stereotactic Biopsy for Recurrent High-Grade Glioma
Status:
Completed
Trial end date:
2007-04-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Collecting fluid from a brain tumor using a small catheter may help doctors learn
how much methotrexate gets into the tumor to kill the tumor cells. It may also help doctors
learn how methotrexate works in the brain and in the rest of the body.
PURPOSE: This clinical trial is studying how much methotrexate gets into the brain tumor by
collecting fluid directly from the tumor through a small catheter in patients undergoing
stereotactic biopsy for recurrent high-grade glioma.