Pharmacokinetics of Posaconazole Prophylaxis in Acute Leukemia
Status:
Completed
Trial end date:
2013-09-01
Target enrollment:
Participant gender:
Summary
The goal of this clinical research study is to learn the amount of posaconazole that is in
the body at different time points when given to patients with leukemia. The safety of this
drug will also be studied.
Objectives:
Primary:
To study the plasma pharmacokinetics of posaconazole in patients with newly diagnosed acute
myelogenous leukemia (AML) or high-risk myelodysplastic syndrome (HR-MDS) undergoing
induction chemotherapy or relapsed or refractory patients who will receive salvage
chemotherapy.
Secondary:
To evaluate the safety of posaconazole given as prophylaxis.