Pharmacokinetics of Miltefosine in Children and Adults
Status:
Completed
Trial end date:
2015-12-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to determine the pharmacokinetics of miltefosine in children and
adults with cutaneous leishmaniasis in plasma and intracellularly, and its relation with the
parasitologic response. The results will provide pharmacologic bases to optimize the use of
miltefosine for the treatment of cutaneous leishmaniasis, and will provide the knowledge base
to assess the impact of pharmacokinetic behavior in children and adults on the emergence of
drug resistance.
Phase:
Phase 4
Details
Lead Sponsor:
Centro Internacional de Entrenamiento e Investigaciones Médicas
Collaborator:
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)