Pharmacokinetics of Immunosuppressants in Renal Transplant Candidates Who Have Undergone Laparoscopic Sleeve Gastrectomy
Status:
Completed
Trial end date:
2015-02-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to evaluate how quickly and to what extent different
immunosuppressants are absorbed into the blood (this is called pharmacokinetics) in renal
transplant candidates who have undergone a laparoscopic sleeve gastrectomy. The immune system
is the body's defense against diseases. It also attacks "foreign" tissues such as a
transplanted kidney. Immunosuppressant medications such as Astagraf sustained release (XL),
Prograf, and mycophenolate mofetil may be given to suppress the immune system following
kidney transplantation and prevent rejection of a transplanted kidney. This study is being
performed to determine if patients who undergo laparoscopic sleeve gastrectomy need different
doses of immunosuppressant medications.