Pharmacokinetics of Advantage Anti-Caries Varnish

• Status: Completed
• Trial end date: 2018-04-25
• Target enrollment: 0
• Participant gender: All

Summary

The study aim is to characterize the kinetics of iodine and fluoride following topical application of a combined PVP-I and NaF anti-dental caries varnish in healthy adults.

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Advantage Silver Dental Arrest, LLC
• Collaborator: University of Washington
• Treatments: Imidacloprid

Criteria

Inclusion Criteria:

• Healthy adults 18 y and older, at least 20 teeth, not taking prescription or OTC medications.

Exclusion Criteria:

• Pregnant, weighed less than 110 pounds, had oral mucositis, ulcerative lesions, sensitivity to shellfish or iodine or fluoride varnish, or had known hypothyroidism, hyperthyroidism, dermatitis herpetiformis, hypocomplementemic vasculitis, nodular thread with heart disease, multi nodular goiter, Graves disease, or autoimmune thyroiditis