Pharmacokinetics and Pleural Fluid Penetration of Amoxicillin and Clavulanic Acid in Patients With Pleural Infections
Status:
Recruiting
Trial end date:
2022-04-01
Target enrollment:
Participant gender:
Summary
The incidence of pleural infection is increasing worldwide since the last two decades.
Antibiotics are one of the cornerstones of the treatment of this disease and must be
associated to a correct evacuation of the pleural effusion.
Data concerning the pleural diffusion of antibiotics currently used in community acquired
pleural infection are scarce. The main objective of this study is to evaluate the pleural
pharmacokinetic of amoxicillin and clavulanic acid in patients with a complicated pleural
infection (patients who need a chest tube insertion).