Pharmacokinetics and Pharmacodynamics of an Anti-HIV Drug in Israeli Ethiopian and Non-Ethiopian Populations
Status:
Withdrawn
Trial end date:
2007-09-01
Target enrollment:
Participant gender:
Summary
The objective of this proposal is based on the assumption that the HIV infected Ethiopian
population responded in a different way in comparison to the Caucasian subjects to Lopinavir
therapy. Our preliminary data demonstrated that Ethiopian's have different Lopinavir serum
concentration in comparison to non-Ethiopian's. For these reasons the plan of this study is
to investigate the pharmacokinetic/pharmacodynamic (PK/PD) profile in both populations. The
results will allow to establish a better personalised medicine for HIV infected individuals.