Pharmacokinetics and Pharmacodynamics of Sugammadex in Reversal of Vecuronium-induced Neuromuscular Blockade

• Status: Active, not recruiting
• Trial end date: 2020-07-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to illustrate pharmacokinetics and pharmacodynamics of sugammadex in reversal of vecuronium-induced neuromuscular blockade in anesthesia obese patients undergoing bariatric surgery.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Guangzhou General Hospital of Guangzhou Military Command
• Treatments: Vecuronium Bromide

Criteria

Inclusion Criteria:

• ASA: Ⅰ~Ⅲ

• BMI≥25kg/m²

• Patients receiving bariatric surgery.

Exclusion Criteria:

• Pregnant or lactating women

• Neuromuscular diseases

• Malignant hyperthermia or allergic history during general anesthesia

• Drugs that react with rocuronium and vecuronium were taken