Pharmacokinetics and Pharmacodynamics of Nasally Applied Esketamine

• Status: Completed
• Trial end date: 2009-10-01
• Target enrollment: 0
• Participant gender: Male

Summary

The purpose of this study is the determination of blood concentration and the effectiveness of esketamine after nasal application.

• Phase: Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University Hospital, Basel, Switzerland
• Treatments: Esketamine

Criteria

Inclusion Criteria:

• male

• age ≥18 years ≤ 45 years

• healthy

• non-smoking

• BMI 18-27

Exclusion Criteria:

• abuse of drugs

• known or supposed hypersensitivity and/or contraindication against ketamine or additives

• participation of another clinical study within the last 30 days

• chronic obstructed nose breathing or nasal polyps

• dug allergy

• blood donation within the last two months