Pharmacokinetics and Pharmacodynamics of 3 Dosages of Estriol After Continuous Vaginal Administration for 21 Days
Status:
Completed
Trial end date:
2017-06-06
Target enrollment:
Participant gender:
Summary
This clinical trial evaluated the pharmacokinetics and pharmacodynamics of estriol in healthy
post-menopausal women after the application of one vaginal ring containing one of three
different dosages of estriol (100 mg (Test 1), 300 mg (Test 2) or 600 mg (Test 3)) with
continuous delivery (0.125, 0.250 or 0.500 mg/day) for 21 days. And also, characterized its
safety and tolerability.