Pharmacokinetics and Excretion of Albendazole and Its Metabolites in Saliva
Status:
Not yet recruiting
Trial end date:
2022-12-16
Target enrollment:
Participant gender:
Summary
This project will develop and assess the feasibility and acceptability of a salive-based
assay to monitor adherence to Mass Drug Administration (MDA) campaigns within
Soil-transmitted helminthiasis (STH) control programs, evaluating the salive and serum
pharmacokinetics of ALBENDAZOLE (ABZ) and its metabolites.The final goal is to obtain a field
ready tool for the measurement of adherence to anthelmintic treatment at a community level
that serves as a coverage/adherence indicator and a reference standard for other monitoring
tools.