Pharmacokinetics Study of Asciminib in Subjects With Impaired Renal Function Compared to Matched Healthy Volunteers
Status:
Completed
Trial end date:
2019-04-14
Target enrollment:
Participant gender:
Summary
The purpose of this study is to characterize the pharmacokinetics (PK) and safety profile of
asciminib following a single oral dose in adult subjects with renal impairment compared to a
matched group of healthy subjects with normal renal function.
The results will determine whether or not a dose adjustment should be recommended when
treating patients with asciminib who have impaired renal function.