Pharmacokinetics Study of AMG 423 in Healthy Subjects and Subjects With Various Degrees of Renal Insufficiency
Status:
Completed
Trial end date:
2013-05-01
Target enrollment:
Participant gender:
Summary
A phase 1, open-label study in subjects with normal renal function and subjects with various
degrees of renal insufficiency, including patients with end-stage renal disease (ESRD)
requiring hemodialysis. The primary objective is to evaluate the single-dose PK of AMG 423 in
subjects with various degrees of renal insufficiency, including patients with end-stage renal
disease requiring hemodialysis.