Pharmacokinetics, Safety, and Lung Deposition of 99mTc-DTPA Delivered Via the EDDIS System in Healthy Volunteers

• Status: NOT_YET_RECRUITING
• Trial end date: 2026-09-21

Summary

Device:

EDDIS-IDDS (Enhanced Digital Dose Inhalation Delivery System) - a portable, breath-actuated, digitally monitored system for precision delivery of inhaled agents with automated recording of inspiratory volume, flow, duration, and breath-hold parameters.

Drug:

99mTc-DTPA (technetium-99m diethylenetriaminepentaacetic acid) - administered in aqueous solution (0.9% NaCl), radiolabeled for gamma scintigraphic imaging.

Total dose: 500-800 Ci in 2 ml solution.

Administration:

Single-dose inhalation under supervision in a clinical setting.

• Phase: PHASE1

Details

• Lead Sponsor: Andrey Petrov
• Collaborator: Ruslan Lytvin