Pharmacokinetics, Safety, Tolerability and Efficacy of Intravenous Doses of ZGN-433 in Obese Female Volunteers

• Status: Completed
• Trial end date: 2011-11-01
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of this study is to assess whether multiple doses of ZGN-433 are safe and effective.

• Phase: Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Zafgen, Inc.
• Treatments: CKD732

Criteria

Inclusion Criteria:

• Obese but otherwise healthy females

• Non-childbearing potential (surgically sterile, post-menopausal, or receiving implanted or injectable contraceptive for at least 3 months)

• BMI ≥ 30 and ≤ 50 kg/m2

• Stable body weight during the past month

Exclusion Criteria:

• Use of weight loss agents in the past month

• History of eating disorder

• History of gastric bypass surgery

• Current smokers