Pharmacokinetic and Exploratory Electrocardiogram (ECG) Study
Status:
Completed
Trial end date:
2008-01-01
Target enrollment:
Participant gender:
Summary
This study will characterize the pharmacokinetics of colchicine after an oral dosing regimen
of 4.8 mg over 6 hours. In addition it will compare the electrocardiogram (ECG) changes, if
any, from this dosing regimen to that of a single dose of moxifloxacin 400 mg, a positive
control for the corrected QT interval (QTc) prolongation.
Phase:
Phase 1
Details
Lead Sponsor:
Mutual Pharmaceutical Company, Inc.
Treatments:
Colchicine Moxifloxacin Norgestimate, ethinyl estradiol drug combination