Pharmacokinetic and Drug Interaction Study of Red Yeast Rice Capsules
Status:
Completed
Trial end date:
2011-04-01
Target enrollment:
Participant gender:
Summary
Red yeast rice capsule (LipoCol Forte)is a nature product that has been demonstrated a
significant cholesterol lowering effect which might be caused by addictive and/or synergistic
effects of lovastatin (monacolin K) with other monacolins and substances in capsules. The
usual dose of red yeast rice capsule(LipoCol Forte)for hypercholesterolemia is one capsule
twice/day.
However, the pharmacokinetic profile of red yeast rice capsule (LipoCol Forte)is still
unknown.
The objective of the study is to evaluate the pharmacokinetic profile of red yeast rice
capsule (LipoCol Forte) after administering single and multiple dose to healthy subjects.