Pharmacokinetic Study to Evaluate Dabigatran Etexilate in Elderly Subjects
Status:
Recruiting
Trial end date:
2023-07-30
Target enrollment:
Participant gender:
Summary
This study intends to collect blood samples of adult healthy subjects, elderly healthy
subjects and elderly patients with atrial fibrillation after taking dabigatran etexilate for
pharmacokinetics and other studies, aiming to reveal the effect of dabigatran etexilate in
Chinese elderly population. Pharmacokinetic profile and biomarker concentration levels; fecal
samples were collected for gut microbiota studies to further explore potential mechanisms.
The results of the study may provide reference for the precision medicine of dabigatran
etexilate and other drugs in the elderly population or the development of new clinical drugs.