Overview

Pharmacokinetic Study of Pitavastatin and Ritonavir-Boosted Darunavir or Efavirenz

Status:
Completed
Trial end date:
2013-01-01
Target enrollment:
Participant gender:
Summary
The main goal of this study is to determine how taking efavirenz affects the levels of pitavastatin in the bloodstream when both drugs are taken together and to see how darunavir with ritonavir affects the levels of pitavastatin in the bloodstream. Secondary goals are to see how taking pitavastatin affects the levels in the blood of efavirenz when both drugs are taken together and to see how taking pitavastatin affects the levels in the blood of darunavir.
Phase:
Phase 1
Details
Lead Sponsor:
New York University School of Medicine
NYU Langone Health
Collaborators:
Bellevue/NYU AIDS Clinical Trials Unit
Kowa Pharmaceuticals America, Inc.
New York City Health and Hospitals Corporation
University at Buffalo
Treatments:
Darunavir
Efavirenz
Pitavastatin
Ritonavir