Pharmacokinetic Study of Indinavir Drug Levels When Boosted With Ritonavir in Thailand

• Status: Completed
• Trial end date: 2010-08-01
• Target enrollment: 0
• Participant gender: All

Summary

This study looks at the ways indinavir drug levels, when boosted with ritonavir, may vary from patient to patient. The study population are HIV+ Thai individuals.

• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Harvard School of Public Health; Harvard School of Public Health (HSPH)
• Collaborator: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
• Treatments: Indinavir; Ritonavir

Criteria

Inclusion Criteria:

• Subjects enrolled in the parent study, "Monitoring HAART Therapy in HIV-Infected Patients in Thailand (PHPT-3)" and agreeing to additional blood sampling and tests.

Exclusion Criteria:

• Current active substance or alcohol abuse

• Active opportunistic infection

• Chronic malabsorption or diarrhea

• Other clinically significant disease

• Certain lab values (e.g. hemoglobin < 8.0 mg/dL)