Pharmacokinetic Study of Antiretroviral Drugs and Related Drugs During and After Pregnancy
Status:
Completed
Trial end date:
2020-09-30
Target enrollment:
Participant gender:
Summary
The purpose of this study is to evaluate the pharmacokinetics (PKs) of antiretroviral (ARV)
and tuberculosis (TB) medications in pregnant women and their infants. (Pharmacokinetics are
the various interactions between a drug and the body.) This study will also evaluate the PKs
of certain ARVs in postpartum women before and after starting hormonal contraceptives. The
PKs of these drugs will be evaluated by measuring the amount of medicine present in blood
and/or vaginal secretions.
Details
Lead Sponsor:
National Institute of Allergy and Infectious Diseases (NIAID)
Collaborator:
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)