Pharmacokinetic Evaluation of Intranasal Nalmefene
Status:
Completed
Trial end date:
2021-05-24
Target enrollment:
Participant gender:
Summary
This study is to determine the pharmacokinetics (how the body absorbs, breaks down and
eliminates drug from your body) of nalmefene when given intranasally (IN;into the nose)
compared to a dose of nalmefene when given intramuscularly (IM; into the muscle); to compare
the blood levels of nalmefene when given IN to nalmefene when given IM; and to evaluate the
safety and tolerability of nalmefene IN.