Overview

Pharmacokinetic Drug Interactions Between Single and Concomitant Administrations of Amlodipine, Losartan, and Hydrochlorothiazide in Subjects With (Pre)Hypertension

Status:
Completed

Trial end date:
2011-03-01

Target enrollment:

Participant gender:

Summary

This study is aimed to evaluate the pharmacokinetics and the drug-drug interaction among anti-hypertension drugs-amlodipine, losartan, and hydrochlorothiazide. This pilot study provides useful information to develop a new fixed dose combination drug.

Phase:

Phase 1

Details

Lead Sponsor:

Yonsei University

Treatments:

Amlodipine
Hydrochlorothiazide
Losartan