Pharmacokinetic Drug Interaction Study of Dapagliflozin and Valsartan or Simvastatin in Healthy Subjects
Status:
Completed
Trial end date:
2009-03-01
Target enrollment:
Participant gender:
Summary
Phase A - To assess the effect of simvastatin on the pharmacokinetics (PK) of dapagliflozin
and to determine the effect of dapagliflozin on the PK of simvastatin, when simvastatin and
dapagliflozin are coadministered in healthy subjects. Phase B - To assess the effect of
valsartan on the PK of dapagliflozin and to determine the effect of dapagliflozin on the PK
of valsartan, when valsartan and dapagliflozin are coadministered in healthy subjects