Overview

Pharmacokinetic Boosting of Osimertinib

Status:
Recruiting
Trial end date:
2021-12-31
Target enrollment:
Participant gender:
Summary
The main objective of this study is to evaluate if systemic exposure of osimertinib (i.e. AUC) is increased when osimertinib is co-administered with cobicistat in patients with relatively low plasma trough concentration while receiving the standard osimertinib dose.
Phase:
Early Phase 1
Details
Lead Sponsor:
Academisch Ziekenhuis Maastricht
Collaborators:
The Netherlands Cancer Institute
ZonMw: The Netherlands Organisation for Health Research and Development
Treatments:
Cobicistat
Osimertinib