Pharmacokinetic Analysis of High Dose Methotrexate in Pediatric Lymphoblastic Malignancies
Status:
Completed
Trial end date:
2010-02-01
Target enrollment:
Participant gender:
Summary
* The pharmacokinetics of MTX were assessed with regards to the relevance of several
different patient specific factors in 291 pediatric patients, who were administered with high
dose of MTX. Population pharmacokinetics of MTX analysis was performed by using nonlinear
mixed effects modeling.
Phase:
N/A
Details
Lead Sponsor:
The Children's Hospital of Zhejiang University School of Medicine