PharmacofMRI of Anxiolytic Medications (Pregabalin)
Status:
Completed
Trial end date:
2008-12-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to use functional magnetic resonance imaging (fMRI) in healthy
controls to examine the acute effects of certain anxiolytic medications on brain function. In
this case, the medication pregabalin will be used. The investigators hypothesize that
pregabalin (at doses of 50 mg and 200 mg, versus placebo) will yield a reduction in amygdala
and insula activity (in a dose-dependent fashion) during emotion processing using fMRI.