Pharmacodynamics and Pharmacokinetics of Insulin Detemir in Subjects With Type 2 Diabetes

• Status: Completed
• Trial end date: 2003-06-01
• Target enrollment: 0
• Participant gender: All

Summary

This trial is conducted in Europe. The aim of this trial is to investigate the pharmacodynamics and pharmacokinetics of single doses of insulin detemir and insulin NPH in subjects with type 2 diabetes.

• Phase: Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Novo Nordisk A/S
• Treatments: Insulin; Insulin Detemir; Insulin, Globin Zinc; Insulin, Isophane; Isophane insulin, beef; Isophane Insulin, Human

Criteria

Inclusion Criteria:

• Type 2 diabetes

• Subjects treated with insulin for minimum 3 months

• Duration of diabetes for at least 12 months

• Body Mass Index (BMI) below 30 kg/m^2

• HbA1c maximum 10% based on analysis from central laboratory

Exclusion Criteria:

• Current treatment with insulin above 1.2 U/kg/day

• Current treatment with insulin glargine

• Current treatment with drugs known to interfere with glucose metabolism

• Current treatment with oral antidiabetic drugs