Pharmacodynamics and Arteriovenous Differences of Naloxone in Healthy Participants Exposed to an Opioid
Status:
Completed
Trial end date:
2016-02-01
Target enrollment:
Participant gender:
Summary
Overdose with potential deadly outcome is a serious problem among opioid abusers, not least
in Norway. To save lives, immediate treatment with a μ-opioid antidote such as naloxone is
required. The purpose of this study is to explore the pharmacokinetics and pharmacodynamics
of naloxone in healthy volunteers under opioid influence.