Pharmacodynamics, Pharmacogenetics, Clinical Efficacy and Safety of Tradipitant for Functional Dyspepsia

• Status: Not yet recruiting
• Trial end date: 2025-12-01
• Target enrollment: 0
• Participant gender: All

Summary

To evaluate the effects of tradipitant relative to placebo on gastric motor functions, satiation, and postprandial symptoms in patients with functional dyspepsia.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Vanda Pharmaceuticals
• Collaborator: Mayo Clinic

Criteria

Inclusion Criteria:

• Able to provide written consent

• Body Mass Index (BMI) of 18-35 kg/m2

• Absence of other diseases which could interfere with interpretation of study results

Exclusion Criteria:

• Current H. pylori infection

• Pregnancy or nursing

• Recent history of Alcohol Use Disorder or Substance Use Disorder