Pharmacodynamic Interactions of Propofol and Dexmedetomidine on Intravenous Anesthesia

• Status: Completed
• Trial end date: 2016-07-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine pharmacodynamic interactions of propofol and dexmedetomidine,exploring the effect of dexmedetomidine on propofol unconsciousness median effective concentration (EC50).

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Guangzhou General Hospital of Guangzhou Military Command
• Treatments: Anesthetics; Dexmedetomidine; Propofol

Criteria

Inclusion Criteria:

1. Weight:18≦ BMI≦25

2. Written informed consent from the patient or the relatives of the participating patient.

Exclusion Criteria:

1. A previous history of intolerance to the study drug or related compounds and additives.

2. Existing significant haematological, endocrine, metabolic or gastrointestinal disease.