Pharmacodynamic Clinical Trial of Cardiovascular Polypill on LDL Cholesterol
Status:
Terminated
Trial end date:
2012-04-01
Target enrollment:
Participant gender:
Summary
This study evaluates the effect on LDL cholesterol of the 3 drugs given together in the
cardiovascular fixed dose combination pill (acetylsalicylic acid, simvastatin, and ramipril)
as compared to the effect on LDL cholesterol of the reference products (simvastatin,
ramipril, acetylsalicylic acid) Approximately 350 subjects will be screened, 266 randomized
in order about 238 subjects to finish the study.