Ph1 Lobeline Interaction Study - 1

• Status: Unknown status
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of this study is to determine if there are significant cardiovascular or other interactions between sublingual lobeline and intravenous methamphetamine.

• Phase: Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: National Institute on Drug Abuse (NIDA)
• Treatments: Lobeline

Criteria

Inclusion Criteria:

• Be between the ages of 18 and 45 years of age

• Be in general good health with a history of methamphetamine (MA) abuse (but not dependence)

• If female and of child bearing potential, agrees to use birth control

• Be able to understand and provide written informed consent

• Have a body mass index between 18 and 30

• Have reported use of (MA) during the past three months without experiencing adverse consequence plus a life time MA or amphetamine use history of at least four occasions of use

• Have a negative drug test (barbiturates, benzodiazepines, amphetamines, opiates, cocaine, cannabinoids, ethanol) at screening and at the time of admission

Exclusion Criteria:

• Please contact site for details