Ph I Study of Lithium During Whole Brain Radiotherapy For Patients With Brain Metastases
Status:
Terminated
Trial end date:
2009-03-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. Drugs, such as
lithium, may protect normal cells from the side effects of radiation therapy. Giving lithium
together with radiation therapy may allow a higher dose of radiation therapy to be given so
that more tumor cells are killed.
PURPOSE: This phase I trial is studying the side effects and best dose of lithium when given
together with whole-brain radiation therapy in treating patients with brain metastases from
primary cancer outside the brain.