Overview

Personalized Antisense Oligonucleotide for A Single Participant With ATN1 Gene Mutation

Status:
ACTIVE_NOT_RECRUITING
Trial end date:
2026-11-01
Target enrollment:
Participant gender:
Summary
This research project entails delivery of a personalized antisense oligonucleotide (ASO) drug designed for a single participant with dentatorubral-pallidoluysian atrophy (DRPLA) due to a heterozygous pathogenic CAG trinucleotide expansion in ATN1
Phase:
PHASE1
Details
Lead Sponsor:
n-Lorem Foundation
Collaborator:
Hawaii Pacific Neuroscience