Peritoneal Lavage Using Saline or Saline With Ondansetron for Pain Control After Laparoscopic Cholecystectomy

• Status: NOT_YET_RECRUITING
• Trial end date: 2025-12-31

Summary

This is a pilot clinical trial evaluating whether adding ondansetron to a peritoneal lavage with saline during laparoscopic cholecystectomy can reduce postoperative pain and nausea. Thirty-two adult patients undergoing elective gallbladder removal will be randomly assigned to receive either a standard saline lavage or a saline solution with ondansetron (8 mg) applied directly to the abdominal cavity at the end of surgery. Both groups will receive standard multimodal pain management. The study aims to compare pain levels, incidence of nausea and vomiting, and quality of sleep within the first 24 hours after surgery. Results will help determine if this technique can improve postoperative recovery and patient comfort.

• Phase: PHASE4

Details

• Lead Sponsor: Instituto Mexicano del Seguro Social
• Treatments: Ondansetron; Saline Solution; Sodium Chloride