Perioperative Lidocaine Administration in Thoracoscopic Surgery for Improved Postoperative Pain Control

• Status: Recruiting
• Trial end date: 2022-12-01
• Target enrollment: 0
• Participant gender: All

Summary

Placebo-controlled study to analyze the effect of perioperative intravenous lidocaine administration on total morphine consumption (TMC) and on pain intensity in thoracoscopic surgery .

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Hospital, Basel, Switzerland
• Treatments: Lidocaine

Criteria

Inclusion Criteria:

• Patients undergoing video-assisted thoracoscopic procedures under general anaesthesia.

• American Society of Anesthesiologists (ASA) physical Status classes I to III

• age ≥ 18 years

• Patient informed consent

Exclusion Criteria:

• Contraindications to the class of drugs under study, e.g. known hypersensitivity or allergy to class of drugs or the investigational product

• Contraindications to self-administration of opioids

• Women who are pregnant or breast feeding

• Steroid therapy

• Chronic pain therapy

• Atrioventricular block grade II to III

• Congestive heart failure

• Liver insufficiency

• Known or suspected non-compliance, drug or alcohol abuse

• Inability to follow the procedures of the study, e.g. due to language problems, psychological disorders, dementia

• Participation in another study with investigational drug within the 30 days preceding and during the present study,

• Enrolment of the investigator, his/her family members, employees and other dependent persons