Perioperative Inflammation and Cyclooxygenase 2 (COX-2)
Status:
Completed
Trial end date:
2006-01-01
Target enrollment:
Participant gender:
Summary
Surgery initiates a complex cascade of events involving the release of chemical compounds
from nerve endings and damaged tissue which leads to an inflammatory and pain response. The
purpose of this investigation is to measure various chemical mediators in the blood and
cerebrospinal fluid, and to test the hypothesis that they will be decreased in patients
treated with a COX-2 inhibitor.