Perioperative Fluid Therapy With Balanced Crystalloids
Status:
Completed
Trial end date:
2014-12-01
Target enrollment:
Participant gender:
Summary
Introduction: The strategy of perioperative fluid therapy has an important impact not only on
the circulating volume and perfusion of organs and tissues but also on the patient's internal
environment. The study aimed at comparing the effects of perioperatively administered
balanced crystalloid infusion solutions containing different amounts of metabolizable anions
on homeostasis.
Methods: In the prospective randomized study, patients were assigned to Plasmalyte (PL) and
Ringerfundin (RF) Groups after their postoperative transfer to an intensive care unit (ICU).
The infusion solutions were parenterally administered at 1000 mL/6 hours. Arterialized
capillary blood was sampled at the time of transfer to the ICU (Time 0), and again at 2 hours
and 6 hours from Time 0. The collected blood was tested for blood gas parameters using the
Astrup method.