Perioperative Colloid vs Crystalloid in Patients Undergoing Colorectal Surgery

• Status: Terminated
• Trial end date: 2015-04-01
• Target enrollment: 0
• Participant gender: All

Summary

The primary purpose of this study is to determine the effect of a balanced 6%hydroxyethyl starch 130/0.4 vs. a balanced crystalloid in colorectal surgery. The intraoperative fluid management will be given to optimize the stroke volume variation <= 12%.

The investigators hypothesize that patients in the intervention group will need less fluid administration be optimal hemodynamic stabilized.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Hospital Muenster
• Collaborator: Fresenius Kabi
• Treatments: Hydroxyethyl Starch Derivatives

Criteria

Inclusion Criteria:

• patients undergoing elective colorectal surgery

• minimum age 18 years

• informed consent

Exclusion Criteria:

• patients with severe cardiomyopathy or severe heart failure

• history of coagulation disorders

• intracranial hemorrhage

• patients with severe cardiovascular or respiratory disorders

• renal insufficiency

• severe liver diseases