Perioperative Chemotherapy in Treating Patients With Colon Cancer That Can Be Surgically Removed
Status:
Terminated
Trial end date:
2015-04-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so
they stop growing or die. Combining more than one drug and giving drugs in different ways may
kill more tumor cells. It is not yet known if surgery is more effective with or without
chemotherapy for colon cancer.
PURPOSE: Randomized phase III trial to evaluate whether perioperative 5-Fluorouracil (5-FU)
chemotherapy after curative resection could improve overall survival and disease-free
survival in patients with Duke's B3 or C colon cancer.
Phase:
Phase 3
Details
Lead Sponsor:
ECOG-ACRIN Cancer Research Group
Collaborators:
American College of Surgeons Cancer and Leukemia Group B National Cancer Institute (NCI) NSABP Foundation Inc Southwest Oncology Group