Perineural Versus Systemic Dexamethasone to Prolong Regional Anesthesia in Front Foot Surgery

• Status: Completed
• Trial end date: 2017-05-23
• Target enrollment: 0
• Participant gender: All

Summary

Both perineural and systemic dexamethasone administration allows an increase in analgesic duration of regional anesthesia.

There is a lack of data to determine wich route allows a longer analgesic effect.

This study aims to determine wether perineural dexamethasone allows a longer analgesic duration than systemic route in combination with regional anesthesia (Ropivacaine 0.375%) for front foot surgery.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Hospital, Clermont-Ferrand
• Treatments: Anesthetics; BB 1101; Dexamethasone; Dexamethasone 21-phosphate; Dexamethasone acetate

Criteria

Inclusion Criteria:

• front foot surgery with metacarpal osteotomy under regional anesthesia

• >18 years old

• consent to participate in the study

Exclusion Criteria:

• refusal to participate

• pregnancy

• feeding

• pre existing neuropathy

• ropivacaine allergy

• paracetamol allergy

• liver failure

• cardiac failure

• ketoprofen allergy

• gastric ulcer within the previous year

• tramadol allergy

• history of epilepsy