Perineural Low-dose Dexamethasone Added to Infraclavicular Block Anesthesia
Status:
Completed
Trial end date:
2017-02-01
Target enrollment:
Participant gender:
Summary
Dexamethasone has an evidence-based indication in postoperative emesis prophylaxy and as a
antiinflammatory steroid. Although the perineural administration is off-label, several
studies recognised its analgetic action as an adjuvant for peripheral nerves blockade,
permitting to reduce the concentration of the local anesthetics and extending the sensory and
motor block.Questions remain concerning the mechanism of action, optimal dose, the
lack/degree of toxicity and the comparison with intravenous administration.The aim of this
prospective randomized controlled study is to investigate the efficacy of analgesia with 4 mg
or 2 mg Dexamethasone added to a combination of ropivacaine 0,5% and lidocaine 1% in vertical
infraclavicular blockade (VIB) anesthesia for upper limb surgery.